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Nebido, also known as Testosterone Undecanoate or Testosterone U, is a slow-acting injectable testosterone that is used to treat hypogonadism in men. Hypogonadism is a condition in which the body does not produce enough testosterone, which can lead to a variety of symptoms including low libido, fatigue, and decreased muscle mass. Nebido is also sometimes used by bodybuilders and athletes to increase muscle mass and strength.

Nebido is different from other testosterone treatments because it is a long-acting injection that is given once every 10-14 weeks. This means that it requires less frequent dosing compared to other testosterone treatments such as testosterone cypionate or enanthate. It is also less likely to cause peaks and troughs in testosterone levels, which can result in mood swings and other side effects.

In Bodybuilding

Nebido is a form of injectable testosterone that is commonly used by bodybuilders for its anabolic effects, which can help in muscle building and enhancing strength. The usual administration of Nebido involves injecting it into the muscle every 10-14 weeks, as it is a long-acting form of testosterone that releases slowly over several weeks. Typically, bodybuilders may use Nebido as part of their steroid cycle, alternating its use during the “off” phase, to help prevent muscle breakdown and maintain muscle mass. However, it is crucial to keep in mind that steroids, including Nebido, can have serious health implications and should only be used under the supervision of a healthcare professional, as their misuse may result in liver damage, hormonal imbalances, and cardiovascular diseases.

Hypogonadism and Nebido

Nebido has been shown to be effective in increasing testosterone levels in hypogonadal men, with one study showing an increase in testosterone levels from an average of 6.9 nmol/L to 13.2 nmol/L after 6 months of treatment. This increase in testosterone levels led to improvements in libido, erectile function, and muscle mass.

While Nebido is primarily used to treat hypogonadism, some bodybuilders and athletes have used it to increase muscle mass and strength. However, it is important to note that the use of Nebido for non-medical purposes is illegal and can result in serious side effects.

Nebido is not without its potential side effects, which can include acne, mood swings, and an increase in red blood cell count. It can also have negative effects on cholesterol levels, and long-term use can increase the risk of cardiovascular disease.

Overall, Nebido is an effective treatment for hypogonadism and can help improve symptoms such as low libido, fatigue, and decreased muscle mass. However, it is important to only use Nebido under the guidance of a medical professional and to avoid using it for non-medical purposes.

Mentions of Nebido (Testosterone U) in journals:

  1. “Long-term testosterone therapy in hypogonadal men ameliorates elements of the metabolic syndrome: an observational, long-term registry study.” European Journal of Endocrinology, 2016.
  2. “Testosterone undecanoate restores erectile function in a subset of patients with venous leakage: a series of case reports.” Andrology, 2016.
  3. “Improvement in sexual function after testosterone therapy in men with hypogonadism: results from the European Male Aging Study.” The Journal of Sexual Medicine, 2016.
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