Description
Methenolone (primobolan) was discovered in 1960. It started making injectable drugs in 1962. Methenolone was initially recommended to address muscle loss following surgery, infections, long-term illnesses, corticosteroid treatment, or starvation, as well as osteoporosis and breast cancer. Methenolone was widely used to help underweight babies gain weight without any adverse effects. Methenolone is an anabolic steroid with mild androgenic action and moderate anabolic impact. Methenolone has a higher binding ability to androgen receptors than testosterone. Adult dosages for aplastic anemia are typically 1–3 mg/kg per day. Hypercalcaemia, accelerated bone growth, and skeletal weight are some of the negative consequences. Men: priapism, azoospermia, hirsutism, baldness, acne, and edema. Women may have virilization, amenorrhoea, irregular periods, decreased breastfeeding, and increased desire. Virilization symptoms may occur in youngsters. The effects of metenolone may be enhanced by anti-diabetic drugs and warfarin. Metenolone may cause neuromuscular blocker resistance and may interfere with glucose tolerance and thyroid function testing. Metenolone enanthate is an ester derivative of methenolone marketed as Primobolan (tablet form) or Primobolan Depot (injectable). It doesn’t make estrogens when it interacts with aromatase. It is utilized by individuals who are sensitive to estrogenic effects, since it is less estrogenic than nandrolone. This property makes primobolan a fat burner. Primobolan doesn’t become estradiol. As an anabolic steroid, metenolone is prohibited in WADA-regulated sports. Nadzeya Ostapchuk of Belarus lost her gold medal after testing positive for metenolone at the 2012 London Olympics. This girl is out of the Olympics. NBA and NBPA Anti-Drug Program prohibited methenolone usage. It was discovered that Hedo Turkolu of the Orlando Magic had tested positive for methenolone in February 2013. Because of the steroid Metenolone, Natalia Volgina lost her 2013 Old Mutual Two Oceans Marathon championship and got a two-year competitive suspension in December 2013.
This medication has similar effects as winstrol but is not harmful to the liver. Primobolan’s methenolone molecule may promote muscle mass growth while burning fat depending on doses.
Overview
Primobolan 100 is a dht-based anabolic steroid. It is an ester derivative of methenolone popularly known as Primobolan (tablet form) (injectable).
It doesn’t make estrogens when it interacts with aromatase. It is utilized by individuals who are sensitive to estrogenic effects, since it is less estrogenic than nandrolone. Methenolone comes in two forms: enanthate and acetate.
The injection has a greater bioavailability. It is a long-acting enanthate ester. It also has a better survival rate since it bypasses hepatic degradation first. The pills are acetate. Oral bioavailability requires 1-methylation, not 17-alkylation. This relieves hepatic stress. It is one of the safest steroids with minimal adverse effects. Methenolone has no estrogenic effects and has no impact on cholesterol levels.
Methenolone is also not excessively suppressive of the hpta axis. So many bodybuilders take it to preserve gains and strength between steroid cycles.
Primobolan:
Before diving into the details of conducting a Primobolan cycle, let’s first define this steroid.
Primobolan is an oral steroid that may also be injected. Despite its anabolic properties, it is often used as a fat-burning steroid.
Unlike other substances, Primobolan causes neither bloating or water retention.
Primobolan’s chemical name is methenolone, and it’s a highly sought-after steroid, even more so than trenbolone or winstrol.
However, when compared to other strong steroids like tren and dianabol, Primobolan is a milder steroid with low androgenic/anabolic scores.
Because it is a weaker molecule, many ‘hardcore’ bodybuilders prefer to utilize more hazardous steroids. But don’t be fooled, Primo may offer you significant benefits when taken properly.
In reality, many old-school bodybuilders from the Golden-Era of bodybuilding (the 1970s and 1980s) used Primobolan to avoid gynecomastia.
It doesn’t aromatize, therefore it doesn’t raise estrogen levels. Excess estrogen causes gyno.
Arnold reportedly utilized primo, helping him become the best Mr Olympia champion ever.
Muscle Gain
Primobolan is mainly a cutting steroid, although it may also be used to gain lean muscle mass.
Primo accomplishes this via increasing muscle nitrogen retention. A positive nitrogen balance is required to establish an anabolic environment in the body where new muscle tissue is created.
It also helps maintain muscle mass while reducing calories, since the body would otherwise become catabolic and start destroying muscle tissue for energy.
Even if you cut…
You can gain muscle on Primobolan if you work hard, eat properly, and use other strong steroids with it.
A primobolan cycle will not develop muscle as much as a dianabol cycle. So don’t expect to develop 20 lbs of lean muscle in 2 weeks. But dianabol won’t burn fat like primo can.
Keep Muscle
Primobolan is often used during reducing cycles to avoid muscle loss, a bodybuilder’s worst fear.
To lose weight, you must be in a calorie deficit.
This implies you must consume less calories per day than your body need to retain its present condition.
To compensate for the shortage of calories, your body uses stored fat. Great!
The issue arises when calories get too low, causing the body to start burning muscular tissue.
Primoblan inhibits muscle catabolism, keeping you large and full throughout your trim.
Fat Burner
Primobolan shines in this situation.
Primo is simply one of the finest fat burners available.
You become a fat-burning machine as your metabolism speeds up.
Obviously, Primobolan isn’t a magic worker, so to maximize its benefits, you’ll need to perform lots of cardio, train properly, and eat properly.
Don’t expect to look like Jeff Seid simply because you’re on steroids if you spend most of your time on the sofa eating garbage and hardly doing out.
But if you exercise and eat properly, you’ll be surprised at the outcomes.
Resuscitates
This following advantage may surprise some.
Steroids are usually viewed negatively due to their perceived risk.
However, Primobolan has been shown to improve the immune system.
Your immune system defends you against sickness and disease, and the stronger it is, the healthier you are.
Taking Primobolan strengthens your immune system, making you healthier and less prone to sickness.
DOSAGE PACKAGING
100mg/ml 10ml vial /box
Description
Metenolone enanthate, or methenolone enanthate, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
Chemical name
[(5S,8R,9S,10S,13S,14S, 17S)-1,10,13-trimethyl-3-oxo- 4,5,6,7,8,9,11,12,14,15, 16,17-dodecahydrocyclopenta [a]phenanthren-17-yl] heptanoate
Synonyms
METHENOLONE ENANTHATE
303-42-4
metenolone enanthate
Primobolan depot
UNII-0SPD480WFH
MeSH Entry Terms
methenolone enanthate
methenolone enanthate, (17alpha)-isomer
methenolone enanthate, (17beta)-isomer
methenolone heptanoate
methenolone oenanthate
Primobolan Depot
Chemical and physical data
Formula
C27H42O3
Molecular Weight
414.630 g·mol−1
Appearance
White to Light yellow powder to crystal
Melting point
289-292°C
Boiling point
504.3±50.0 °C at 760 mmHg
Purity
>98.0%(HPLC)
Density
1.1±0.1 g/cm3
Vapour Pressure
0.0±1.3 mmHg at 25°C
Enthalpy of Vaporization
77.4±3.0 kJ/mol
Index of Refraction
1.526
Molar Refractivity
120.5±0.4 cm3
Flash Point
213.1±30.2 °C
Solubility
Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO,Acetone,etc.
Polar Surface Area
43 Å2
Polarizability
47.8±0.5 10-24cm3
Surface Tension
40.5±5.0 dyne/cm
Molar Volume
392.6±5.0 cm3
Hazard Codes
Xi
Identifiers
CAS Number
303-42-4
IUPAC name
[(5S,8R,9S,10S,13S,14S ,17S)-1,10,13-trimethyl-3-oxo- 4,5,6,7,8,9,11,12,14, 15,16,17-dodecahydrocyclopenta [a]phenanthren-17-yl] heptanoate
UNII
0SPD480WFH
PubChem CID
248271
IUPHAR/BPS
DrugBank
ChemSpider ID
217360
KEGG
D01301
CHEBI
31826
ChEMBL
1889112
InChI
1S/C27H42O3/c1-5-6-7- 8-9-25(29)30-24-13-12-22-21-11-10- 19-17-20(28)16-18(2)27(19,4)23(21)14 -15-26(22,24)3/h16,19,21- 24H,5-15,17H2,1-4H3/t19-,21-,22-,23-,24 -,26-,27-/m0/s1
InChIKey
TXUICONDJPYNPY-FRXWOFFRSA-N
DSSTox Substance ID
DTXSID7046754
CompTox Dashboard
DTXSID7046754
ECHA InfoCard
100.005.584
Smiles
O=C2\C=C(\C)[C@@]3([ C@H]1CC[C@@]4 ([C@@H](OC (=O)CCCCCC) CC[C@H]4[C @@H]1CC[C@H ]3C2)C)C
Canonical SMILES
CCCCCCC(= O)OC1CCC2C 1(CCC3C 2CCC4C3(C(=CC( =O)C4)C)C) C
Isomeric SMILES
CCCCCCC(=O)O[C@H]1CC [C@@H]2[C@@]1(CC[C@H ]3[C@H]2CC[C@@H]4[C @@]3(C(=CC(=O)C4)C)C)C
DOSAGE
PACKAGING
100mg/ml
10ml vial /box
Description
Metenolone enanthate, or methenolone enanthate, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
Chemical name
[(5S,8R,9S,10S,13S,14S, 17S)-1,10,13-trimethyl-3-oxo- 4,5,6,7,8,9,11,12,14,15, 16,17-dodecahydrocyclopenta [a]phenanthren-17-yl] heptanoate
Synonyms
METHENOLONE ENANTHATE
303-42-4
metenolone enanthate
Primobolan depot
UNII-0SPD480WFH
MeSH Entry Terms
methenolone enanthate
methenolone enanthate, (17alpha)-isomer
methenolone enanthate, (17beta)-isomer
methenolone heptanoate
methenolone oenanthate
Primobolan Depot
Chemical and physical data
Formula
C27H42O3
Molecular Weight
414.630 g·mol−1
Appearance
White to Light yellow powder to crystal
Melting point
289-292°C
Boiling point
504.3±50.0 °C at 760 mmHg
Purity
>98.0%(HPLC)
Density
1.1±0.1 g/cm3
Vapour Pressure
0.0±1.3 mmHg at 25°C
Enthalpy of Vaporization
77.4±3.0 kJ/mol
Index of Refraction
1.526
Molar Refractivity
120.5±0.4 cm3
Flash Point
213.1±30.2 °C
Solubility
Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO,Acetone,etc.
Polar Surface Area
43 Å2
Polarizability
47.8±0.5 10-24cm3
Surface Tension
40.5±5.0 dyne/cm
Molar Volume
392.6±5.0 cm3
Hazard Codes
Xi
Identifiers
CAS Number
303-42-4
IUPAC name
[(5S,8R,9S,10S,13S,14S ,17S)-1,10,13-trimethyl-3-oxo- 4,5,6,7,8,9,11,12,14, 15,16,17-dodecahydrocyclopenta [a]phenanthren-17-yl] heptanoate
UNII
0SPD480WFH
PubChem CID
248271
IUPHAR/BPS
DrugBank
ChemSpider ID
217360
KEGG
D01301
CHEBI
31826
ChEMBL
1889112
InChI
1S/C27H42O3/c1-5-6-7- 8-9-25(29)30-24-13-12-22-21-11-10- 19-17-20(28)16-18(2)27(19,4)23(21)14 -15-26(22,24)3/h16,19,21- 24H,5-15,17H2,1-4H3/t19-,21-,22-,23-,24 -,26-,27-/m0/s1
InChIKey
TXUICONDJPYNPY-FRXWOFFRSA-N
DSSTox Substance ID
DTXSID7046754
CompTox Dashboard
DTXSID7046754
ECHA InfoCard
100.005.584
Smiles
O=C2\C=C(\C)[C@@]3([ C@H]1CC[C@@]4 ([C@@H](OC (=O)CCCCCC) CC[C@H]4[C @@H]1CC[C@H ]3C2)C)C
Canonical SMILES
CCCCCCC(= O)OC1CCC2C 1(CCC3C 2CCC4C3(C(=CC( =O)C4)C)C) C
Isomeric SMILES
CCCCCCC(=O)O[C@H]1CC [C@@H]2[C@@]1(CC[C@H ]3[C@H]2CC[C@@H]4[C @@]3(C(=CC(=O)C4)C)C)C
DOSAGE
PACKAGING
100mg/ml
10ml vial /box
Description
Metenolone enanthate, or methenolone enanthate, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.
Chemical name
[(5S,8R,9S,10S,13S,14S, 17S)-1,10,13-trimethyl-3-oxo- 4,5,6,7,8,9,11,12,14,15, 16,17-dodecahydrocyclopenta [a]phenanthren-17-yl] heptanoate
Synonyms
METHENOLONE ENANTHATE
303-42-4
metenolone enanthate
Primobolan depot
UNII-0SPD480WFH
MeSH Entry Terms
methenolone enanthate
methenolone enanthate, (17alpha)-isomer
methenolone enanthate, (17beta)-isomer
methenolone heptanoate
methenolone oenanthate
Primobolan Depot
Chemical and physical data
Formula
C27H42O3
Molecular Weight
414.630 g·mol−1
Appearance
White to Light yellow powder to crystal
Melting point
289-292°C
Boiling point
504.3±50.0 °C at 760 mmHg
Purity
>98.0%(HPLC)
Density
1.1±0.1 g/cm3
Vapour Pressure
0.0±1.3 mmHg at 25°C
Enthalpy of Vaporization
77.4±3.0 kJ/mol
Index of Refraction
1.526
Molar Refractivity
120.5±0.4 cm3
Flash Point
213.1±30.2 °C
Solubility
Soluble in Chloroform, Dichloromethane, Ethyl Acetate, DMSO,Acetone,etc.
Polar Surface Area
43 Å2
Polarizability
47.8±0.5 10-24cm3
Surface Tension
40.5±5.0 dyne/cm
Molar Volume
392.6±5.0 cm3
Hazard Codes
Xi
Identifiers
CAS Number
303-42-4
IUPAC name
[(5S,8R,9S,10S,13S,14S ,17S)-1,10,13-trimethyl-3-oxo- 4,5,6,7,8,9,11,12,14, 15,16,17-dodecahydrocyclopenta [a]phenanthren-17-yl] heptanoate
UNII
0SPD480WFH
PubChem CID
248271
IUPHAR/BPS
DrugBank
ChemSpider ID
217360
KEGG
D01301
CHEBI
31826
ChEMBL
1889112
InChI
1S/C27H42O3/c1-5-6-7- 8-9-25(29)30-24-13-12-22-21-11-10- 19-17-20(28)16-18(2)27(19,4)23(21)14 -15-26(22,24)3/h16,19,21- 24H,5-15,17H2,1-4H3/t19-,21-,22-,23-,24 -,26-,27-/m0/s1
InChIKey
TXUICONDJPYNPY-FRXWOFFRSA-N
DSSTox Substance ID
DTXSID7046754
CompTox Dashboard
DTXSID7046754
ECHA InfoCard
100.005.584
Smiles
O=C2\C=C(\C)[C@@]3([ C@H]1CC[C@@]4 ([C@@H](OC (=O)CCCCCC) CC[C@H]4[C @@H]1CC[C@H ]3C2)C)C
Canonical SMILES
CCCCCCC(= O)OC1CCC2C 1(CCC3C 2CCC4C3(C(=CC( =O)C4)C)C) C
Isomeric SMILES
CCCCCCC(=O)O[C@H]1CC [C@@H]2[C@@]1(CC[C@H ]3[C@H]2CC[C@@H]4[C @@]3(C(=CC(=O)C4)C)C)C
