Description
Drostanolone Propionate Overview
Drostanolone propionate, commonly referred to as masteron, is a synthetic version of an anabolic-androgenic steroid derived from dihydrotestosterone. It was discovered that there are two polymorphs of drostanolone propionate, each with unique crystal structures as revealed by single crystal X-ray diffraction. One of the polymorphs has a single molecule in the asymmetric unit and resides in the P21 space group (Z = 2), while the other has two molecules and is situated in the I2 space group (Z = 4). The third polymorph was solved using a parallax tempering/Monte Carlo approach and further refined with the Rietveld method. This polymorph exhibits an orthorhombic P212121 space group with Z = 4. In all structures, the A, B, and C rings of the steroid possess a chair shape while the D ring has a C13 distorted envelope configuration. Both CLP and tight-binding density functional theory were used to calculate the lattice energy of all polymorphs. To gauge the impact of electron correlation on dimer energy magnitude, local electron correlation techniques were employed. Intermolecular interactions were investigated using SAPT0 energy decomposition and Hirshfeld surfaces.
Propionate was introduced in the early 1970s under the name Masteron. Later, it was also known as Drolban and Masteril. Drostanolone Propionate proved to be a highly effective therapeutic agent, particularly in treating inoperable breast cancer in postmenopausal women. Over time, the chemical’s popularity grew among bodybuilders who found it beneficial for cutting. Today, despite no longer being produced or used for medical purposes, Drostanolone Propionate continues to be a sought-after compound among athletes and bodybuilders, even though its availability has become scarce.
Properties
Drostanolone Propionate, a DHT-derived anabolic steroid, has had its structure modified by the inclusion of a methyl group, preventing the hormone from breaking down. This modification also enables the hormone to act as a time-release anabolic. While some underground labs offer Drostanolone Propionate formulations that require less frequent injections, it’s essential to note that these are not officially sanctioned.
Role and Benefits
Drostanolone Propionate is among the few anabolic steroids that exhibit strong anti-estrogenic properties, making it a suitable countermeasure against the estrogenic effects of other substances. This property made it an effective treatment for breast cancer, particularly for women ineligible for chemotherapy or surgery. Bodybuilders often utilize Drostanolone Propionate during their cycles to mitigate estrogenic effects. While it’s predominantly used during cutting cycles to assist in hardening the physique, its low anabolic and androgenic ratings can be misleading. With DHT being five times more androgenic than testosterone, Drostanolone Propionate can help achieve fat loss, a harder physique, and potentially, strength gains, which can be desirable for athletes not interested in muscle mass increase.
Impact
Drostanolone Propionate is most effective when incorporated into a cutting cycle, showing optimal results in individuals with lower body fat. It’s often employed towards the end of a cycle to aid in competition preparation, helping bodybuilders shed stubborn fat that diet and exercise alone might not eliminate. Additionally, its anti-estrogenic properties enhance the overall physical appearance, giving the physique a natural and defined look. However, for individuals with more than 10% body fat or those significantly overweight, the benefits of Drostanolone Propionate may be less noticeable. On the other hand, athletes seeking to enhance strength without significant weight gain might find Drostanolone Propionate a suitable option, provided they adhere to a strict diet and maintain their weight range. This approach allows them to boost muscular endurance and strength while avoiding unnecessary weight gain.
Despite being a relatively mild bulking agent, Drostanolone Propionate can provide gains comparable to those achieved with Primobolan Depot. Even at higher dosages, neither of these substances is particularly potent. Nevertheless, they can provide modest benefits suitable for individuals seeking minor assistance in losing a few pounds or boosting strength. Moreover, Drostanolone Propionate can be a valuable addition to a steroid stack.
Some users also incorporate Drostanolone Propionate into their bulking stacks due to its fat-burning and anti-estrogenic properties. This helps them avoid weight gain during the off-season. Although weight loss can occur without Drostanolone Propionate, many users prefer its inclusion due to the anti-estrogenic effects it offers when taking higher testosterone doses. It’s worth noting, however, that while Drostanolone Propionate can help reduce estrogenic activity when Nandrolones, Dinabol, or Anadrol are added to the stack, it cannot entirely counteract the estrogenic effects of these substances.
Dosage and Use
Men are recommended to take 300-400 mg of Drostanolone Propionate weekly for optimal results, preferably 100 mg every other day. The cycle duration is typically between 6-8 weeks. While this is not a full cycle, it’s important not to extend Drostanolone Propionate usage beyond 8 weeks.
Women should limit their intake to no more than 100 mg per week, reducing or discontinuing use if virilization symptoms arise, as these can become difficult to reverse once they become noticeable. A dosage of 50 mg per week over 4 to 6 weeks is usually sufficient for female athletes to reap the benefits without suffering from severe side effects.
As a relatively mild anabolic steroid, Drostanolone Propionate provides moderate growth and an increase in overall strength. Remember, the effectiveness of a steroid is not solely determined by the bulk it can produce. For those who are already lean, the benefits of this steroid become quite apparent. Whether your goal is to cut faster or gain strength, understanding what Drostanolone Propionate has to offer can help you decide if it’s the right choice for you.
